Calculate replicate variance weighted averaged Z-scores

Replicate averaged Z-scores is calculated by dividing replicate average coefficient by replicate pooled standard error.

Usage

repVarianceWeightedAvgZscore(pvalues, groups)

Arguments

pvalues

Data frame with 'se' (standard error) and 'coef' (coefficient) columns. Such as in pvalues output of modelGeneExpression .

groups

Factor giving group membership for samples in pvalues.

Value

Numeric matrix of averaged Z-scores. Columns correspond to groups and rows to predictors.